The chemical equation for cellular respiration is:
\[ \text{C}6\text{H}{12}\text{O}_6 + 6\text{O}_2 \rightarrow 6\text{CO}_2 + 6\text{H}_2\text{O} \]
For one glucose molecule (C₆H₁₂O₆), 6 molecules of oxygen (O₂) are required. Therefore, for two glucose molecules, you would need:
\[ 2 \times 6\text{O}_2 = 12\text{O}_2 \]
So, the answer is 12.