If two cells each undergo three rounds of mitosis, you can calculate the total number of cells produced using the formula \(2^n\), where \(n\) is the number of rounds of mitosis.
For two cells:
- After the first round of mitosis, each cell divides into 2, resulting in \(2 \times 2 = 4\) cells.
- After the second round, each of those 4 cells divides into 2, resulting in \(4 \times 2 = 8\) cells.
- After the third round, each of those 8 cells divides into 2, resulting in \(8 \times 2 = 16\) cells.
So, after three rounds of mitosis for both original cells, the total number of cells would be 16.
Therefore, the answer is 16.