To determine how many nucleotide bases are needed to code for the specified amino acid chain, we can follow these steps:
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Identify the amino acids: The amino acids are proline, serine, histidine, threonine, and a stop codon.
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Amino acid to codon conversion: Each amino acid is coded by a specific codon, which is a sequence of three nucleotide bases in mRNA. For the stop codon, it also takes three bases.
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Amino acids and their codons:
- Proline (Pro) is coded by the codons CCU, CCC, CCA, or CCG.
- Serine (Ser) is coded by the codons UCU, UCC, UCA, UCG, AGU, or AGC.
- Histidine (His) is coded by the codons CAU or CAC.
- Threonine (Thr) is coded by the codons ACU, ACC, ACA, or ACG.
- Stop codon is coded by UAA, UAG, or UGA.
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Total bases needed: Each of the four amino acids in the chain requires three bases, and the stop codon also requires three bases:
- For 4 amino acids (3 bases each): \(4 \times 3 = 12\) bases
- For the stop codon (3 bases): \(1 \times 3 = 3\) bases
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Overall total:
- Total bases = 12 (for the amino acids) + 3 (for the stop codon) = 15 bases.
Therefore, 15 nucleotide bases are needed to code for the amino acid chain proline, serine, histidine, threonine, and a stop codon.