The amendment you are referring to likely aligns best with option C:
C. Anti-Federalists supported empowering the states at the expense of the federal government as they believed the states could better protect the rights of the people.
This reflects the Anti-Federalists' belief that a strong federal government could infringe upon individual liberties, and that state governments, being closer to the people, could better safeguard their rights. Anti-Federalists often argued for the protection of individual rights and were wary of a centralized authority that could potentially become tyrannical. They believed local and state governments were more accountable to the people and could protect their rights more effectively than a distant federal government.