To ask what a word means in Spanish, you would say "¿Qué quiere decir . . . ?" or "¿Cómo se dice . . . ?" if you want to know how to say a word or phrase in Spanish.
So, the correct options are:
- ¿Qué quiere decir . . . ? (What does . . . mean?)
- ¿Cómo se dice . . . ? (How do you say . . . ?)
The other options are not correct for asking the meaning of a word.
- ¿Cómo se escribe . . . ? means "How is . . . written?"
- ¿Cómo quiere . . . ? does not fit in this context and translates to "How do you want . . . ?"
So your best choices are the first and third options.