The respiratory system and circulatory system interact closely to ensure oxygen is delivered to tissues and carbon dioxide is removed from the body. In the lungs, oxygen from the air is transferred into the blood, where it binds to hemoglobin in red blood cells. These red blood cells transport the oxygen throughout the body to the cells that need it for metabolism.
Simultaneously, as oxygen is delivered to the tissues, red blood cells pick up carbon dioxide (a waste product of cellular respiration) and transport it back to the lungs. There, carbon dioxide is released from the blood and exhaled out of the body.
This continuous exchange of gases—oxygen intake and carbon dioxide removal—demonstrates the crucial interaction between the respiratory and circulatory systems.