Prohibition had a significant impact on the political atmosphere in the United States, and the most accurate statement from the options provided is:
• It divided the Democratic Party and led to the rise of the Republican Party.
Prohibition, implemented through the 18th Amendment in 1920, caused divisions within the Democratic Party, especially between urban, immigrant, and rural voters, with the latter often favoring the dry or anti-alcohol stance. This division ultimately contributed to the Republican Party gaining influence and eventually winning the presidency during the 1920 election.