George Grenville primarily stirred up the colonists and led to their boycott of British goods by passing the Sugar and Stamp Acts.
The Sugar Act of 1764 aimed to reduce the existing tax on molasses but strengthened enforcement to stop smuggling, while the Stamp Act of 1765 imposed a direct tax on a wide range of printed materials in the colonies, requiring that they carry a tax stamp. These acts were seen as unjust by the colonists, who argued that they were being taxed without representation in Parliament, which led to widespread protests and ultimately boycotts of British goods.
The other options listed, such as the Coercive Acts and the Boston Tea Party, occurred later and were responses to earlier British policies that angered the colonists.