To express the whole number 378 as a product of prime numbers with exponents, we first need to perform the prime factorization of 378.
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Start by dividing 378 by 2 (the smallest prime number): \[ 378 \div 2 = 189 \]
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Next, we factor 189. Since 189 is odd, we divide by the next smallest prime number, which is 3: \[ 189 \div 3 = 63 \]
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We continue factoring 63, and again use 3: \[ 63 \div 3 = 21 \]
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Next, we factor 21 using 3: \[ 21 \div 3 = 7 \]
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Finally, we are left with 7, which is a prime number.
Putting it all together, we have: \[ 378 = 2 \times 3 \times 3 \times 3 \times 7 \] This can also be expressed using exponents: \[ 378 = 2^1 \times 3^3 \times 7^1 \]
Therefore, the correct response that expresses 378 as a product of prime numbers with exponents is: 2⋅3³⋅7.