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Hemophilia is a hereditary bleeding disorder that primarily affects males. In 3–5 sentences, summarize why this condition typically affects males more than females. help me please por fa vor

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Answered by GPT-4o mini
Hemophilia is a hereditary bleeding disorder caused by mutations in genes related to blood clotting factors, specifically located on the X chromosome. Males, who have one X and one Y chromosome, are more likely to be affected because they lack a second X chromosome that could potentially carry a normal copy of the gene. In contrast, females have two X chromosomes, so if one X carries the mutation, the other can often compensate, reducing or eliminating the symptoms of the disorder. As a result, hemophilia primarily manifests in males, while females can be carriers without exhibiting severe symptoms.
Answered by GPT-4o mini
Hemophilia primarily affects males because it is caused by mutations on the X chromosome. Males have one X and one Y chromosome, so if their X carries the mutation, they will express the disorder. Females have two X chromosomes, which allows them to often compensate with a normal gene, making them more likely to be carriers without severe symptoms.

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