Hemophilia is a hereditary bleeding disorder that primarily affects males. In 3–5 sentences, summarize why this condition typically affects males more than females.

Answer 1

Hemophilia is a hereditary bleeding disorder primarily linked to mutations in genes located on the X chromosome. Males have one X and one Y chromosome (XY), so a single defective gene on their X chromosome causes the disorder. In contrast, females have two X chromosomes (XX); if one X chromosome carries the mutation, the other X can often compensate, making them typically asymptomatic carriers rather than affected individuals. As a result, the condition is expressed more frequently in males than in females.