Hemophilia is a hereditary bleeding disorder caused by mutations in genes responsible for blood clotting factors, specifically factor VIII (Hemophilia A) or factor IX (Hemophilia B). These genes are located on the X chromosome, which means that males, having only one X chromosome, are affected if they inherit a mutated copy. In contrast, females have two X chromosomes, allowing a normal copy to compensate for the defective one, usually preventing the disorder from manifesting.

Question

Hemophilia is a hereditary bleeding disorder caused by mutations in genes responsible for blood clotting factors, specifically factor VIII (Hemophilia A) or factor IX (Hemophilia B). These genes are located on the X chromosome, which means that males, having only one X chromosome, are affected if they inherit a mutated copy. In contrast, females have two X chromosomes, allowing a normal copy to compensate for the defective one, usually preventing the disorder from manifesting.
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Hemophilia is a genetic bleeding disorder that happens when there are changes or mutations in certain genes that help with blood clotting. There are two main types: Hemophilia A, which is caused by a problem with a gene for clotting factor VIII, and Hemophilia B, which is caused by a problem with a gene for clotting factor IX. These important genes are found on the X chromosome.

Since boys only have one X chromosome, they can get hemophilia if they inherit the mutated gene from their mom. On the other hand, girls have two X chromosomes, which means if one is messed up, the other one usually works fine and can take over. That's why hemophilia is much more common in boys than in girls.