Glucose can be transported into cells with a glucose/sodium symporter. If the extracellular concentration of sodium is always in excess to that of glucose, which of these manipulations would MOST increase the rate of glucose transport into a cell? A diagram shows a shape with finger-like structures on it. On the ends of some of the structures are openings labeled S G L T 2. A glucose molecule and upper N a superscript plus baseline are shown entering one of the openings labeled S G L T 2. Increase in the extracellular concentration of sodium, increase in the intracellular concentration of sodium, increase in the extracellular concentration of glucose, or increase in the intracellular concentration of glucose.

Answer 1

The most effective manipulation to increase the rate of glucose transport into the cell would be to increase the extracellular concentration of glucose. This would create a larger concentration gradient between the extracellular and intracellular glucose, driving more glucose molecules to enter the cell through the glucose/sodium symporter.