Question

Genetic Variation from Errors Quick Check 1 of 51 of 5 Items Question A DNA segment has base order AGC TTA TCG. Which copy exhibits a frameshift mutation through deletion?(1 point) Responses AGC TTT CG AGC TTT CG AGC TCG AGC TCG TTA TCG TTA TCG AGC TTA TAG AGC TTA TAG Skip to navigation page 12 of 12

Answer 1

To identify which copy exhibits a frameshift mutation due to deletion, we need to understand that a frameshift mutation results from the deletion or addition of a number of nucleotides that is not a multiple of three. This shifts the reading frame of the genomic sequence.

The original DNA segment is: AGC TTA TCG

Now, let's analyze each of the provided responses:

1. AGC TTT CG

   • Deletion of one base (A=T) results in a change in the reading frame.

2. AGC TTT CG

   • Same as above, but no indication of deletion here.

3. AGC TCG

   • Deletion of one base (T), which results in a change in the reading frame.

4. TTA TCG

   • Deletion of the first bases (AGC), which does result in a change but doesn't match the original sequence correctly.

5. AGC TTA TAG

   • Insertion of TAG instead of TCG, doesn't indicate straightforward deletion.

So the best option that shows a frameshift mutation due to a deletion is:

AGC TTT CG (deleting 'A' would result in a frameshift).

Thus the answer is AGC TTT CG.