The theory of spontaneous generation, which posited that living organisms could arise from non-living matter, was historically supported by several observations that seemed to show life emerging spontaneously. Some classical examples include:
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Maggots on decaying meat: It was observed that maggots appeared on rotting meat seemingly without any other source, leading some to believe that the meat itself could generate life.
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Mice from grain: People claimed that if you left a pile of grain undisturbed, it would eventually generate mice.
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Frogs from mud: There were beliefs that frogs could arise from mud or stagnant water during certain seasons.
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Insects in filthy environments: The presence of insects in dirt or decomposing material seemed to support the notion that life could emerge spontaneously from inanimate sources.
These observations were eventually challenged and debunked with scientific experimentation, most notably by Louis Pasteur in the 19th century, who demonstrated that microbes in the air were responsible for contamination and that life does not arise from non-living matter under controlled conditions. This laid the groundwork for the germ theory of disease and the understanding of biogenesis, which states that life arises from pre-existing life.