MCMV FST gene therapy works by introducing a modified form of the Follistatin (FST) gene into the recipient's cells. FST is a protein that inhibits the action of myostatin, a protein that limits muscle growth and development.
Once the modified FST gene is introduced into the recipient's cells, it is transcribed into messenger RNA (mRNA) and then translated into FST protein. The FST protein then works to block the activity of myostatin, allowing for increased muscle growth and development.
This leads to an increase in muscle mass, strength, and overall physical performance in the recipient. The modified FST gene therapy essentially overrides the normal regulatory mechanisms that limit muscle growth, leading to enhanced muscle development.
On a molecular level, the FST protein binds to myostatin and prevents it from interacting with its receptors on muscle cells. This disrupts the signaling pathway that normally inhibits muscle growth, allowing for increased muscle protein synthesis and muscle hypertrophy.
Overall, MCMV FST gene therapy works by altering the molecular interactions within muscle cells to promote muscle growth and development.
explain on a molecular level on how MCMV FST gene therapy works
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