The most accurate comparison of the economies of the Southern and New England colonies would be:
"The economy of the Southern colonies relied on growing cash crops, while the economy of the New England colonies relied on trade."
The Southern colonies focused heavily on agriculture and the production of cash crops such as tobacco, rice, and indigo, which were labor-intensive and often dependent on enslaved labor. In contrast, the New England colonies had a more diverse economy that included trade, fishing, shipbuilding, and small-scale farming, as their shorter growing season and rocky soil were less suited for large-scale agriculture.