The correct comparison between a virus and a unicellular organism is:
Unicellular organisms have a cell membrane made from a lipid bilayer; viruses have a protein coat.
This statement accurately highlights the structural differences between viruses and unicellular organisms (which include bacteria, protists, and others). Unicellular organisms possess a cellular structure with a lipid bilayer membrane, while viruses consist of genetic material surrounded by a protein coat (capsid) and lack a cellular membrane.
The other responses contain inaccuracies regarding energy needs, responses to stimuli, and reproduction methods. Viruses do not require energy in the same way living organisms do, they do not respond to stimuli in the same capacity as living cells, and they reproduce by hijacking the host cell's mechanisms rather than through asexual reproduction themselves.