To calculate \( 6.25 \times 10^6 - 4.73 \times 10^6 \), we first recognize that both terms are in the form of \( a \times 10^n \), where \( n = 6 \).
We can subtract the coefficients (the \( a \) values) while keeping the common power of ten:
\[ (6.25 - 4.73) \times 10^6 \]
Calculating the difference of the coefficients:
\[ 6.25 - 4.73 = 1.52 \]
Thus, we have:
\[ 1.52 \times 10^6 \]
Now, we need to express our answer in scientific notation, ensuring it is to 2 decimal places.
The final answer is:
\[ \boxed{1.52 \times 10^6} \]