To calculate \( 6.25 \times 10^6 - 4.73 \times 10^6 \), we can first combine the coefficients since they have the same power of ten.
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Subtract the coefficients: \[ 6.25 - 4.73 = 1.52 \]
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Since both numbers are multiplied by \( 10^6 \), we can keep that part: \[ 1.52 \times 10^6 \]
Now, we express the final answer in scientific notation, which is already in the proper form.
Therefore, the answer is: \[ \boxed{1.52 \times 10^6} \]