The best description of the major group of macromolecules that is protecting Brett's car after it has been washed and waxed is:
C. Lipids are protecting his car because their nonpolar nature makes them insoluble in water.
Here's why this choice is correct: The wax used on cars is primarily made up of lipids, which possess a nonpolar character that makes them water-repellent. This property allows water to bead on the surface rather than adhering to it, thus protecting the paint from water damage and other weather effects. Choices A, B, and D do not accurately reflect the role of macromolecules in the context of car protection.