The correct statement that describes a difference between RNA and DNA is:
Adenine binds with the nitrogen base thymine in DNA while it binds with uracil in RNA.
Here’s a brief explanation of why the other options are incorrect:
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DNA is a single-stranded molecule whereas RNA is a double-stranded molecule in cells. (This is incorrect; DNA is typically double-stranded, while RNA is usually single-stranded.)
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DNA uses ribose while RNA uses deoxyribose as the sugar in the molecule’s backbone. (This is incorrect; DNA uses deoxyribose, while RNA uses ribose.)
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DNA uses phosphate groups to link nucleotides together whereas RNA uses ketone groups. (This is incorrect; both DNA and RNA use phosphate groups to link nucleotides together.)
So, the first response is the accurate difference between RNA and DNA.