Bio question relating to the respiratory tract?

Recent research has shown that cigarette smoke may result in the following:
i.)Destruction of the cilia that line parts of the respiratory system
ii.) Rupturing the walls of the same alveoli
iii.) Thickening of the walls of the bronchioles, thus narrowing their diameter
1V) carbon monoxide competes with binding sites in the alveoli

i am supposed to describe how the smoking of cigarettes interferes with the normal functioning of the respiratory tract for each affect listed above.

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