based on three limitation can you recoomend me one suggested imporvment in a sentence that i can use the limitations are
However, misrepresentation of data is evident, as only 4 out of 26 findings were statistically significant, yet the graph only shows statistically significant cells, omitting the majority of the other data. The variability in haemoglobin γ-expression among different CRISPR clones (gA+gC #65, #68, #73) could indicate inconsistent efficacy. This decreases the validity of the data as it does not provide a complete picture, undermining the significance of the results displayed in the graph. and The limitation of the following graph is that the limited sample size of only two patients makes it difficult to generalise the findings to a larger population since individual variability could significantly influence the observed trends. Furthermore, there was no long-term follow-up since the data ends at 18 months, and therefore long-term trends for HbF levels could not be determined. and The limitation is that specific sample size for each group (HBG1/2 T2, BCL11A T2, KLF1 T1, and control), and variability was not indicated which might not accurately reflect the validity and reduced reliability due to small sample size. The broader scope of focusing on multiple genes rather than a specific gene results in a lack of precision in the study function. No statistical values along with the standard error was included for control sample. This is the current suggested improvment i have but i need one more An improvement that could be made to the studies is increasing the sample size of the experiments and expanding the population that is included, which could increase the generalisability of the studies. This would consequently reduce the random error, yielding more accurate results. In addition, with a greater sample size, the effect of BCL11A inhibition on the prognosis and morbidity of beta-thalassemia can be further analysed, establishing the clinical significance of CRISPR-Cas9.
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