The process that is most likely the target of drugs aimed at reversing or preventing the unregulated reproduction of smooth muscle cells in atherosclerosis is cell division.
Atherosclerosis involves the excessive proliferation of smooth muscle cells, so targeting the mechanisms that control cell division can help to reduce the number of these cells and alleviate the disease. By inhibiting cell division, these drugs can potentially prevent the growth of the plaque that obstructs blood flow in the arteries.