As an extension, CRISPR-Cas9 could be utilised on different genes that affect the pathophysiology of thalassemia, such as HBG1/2 and KLF1. Alteration of several different genes could have synergistic effects on foetal haemoglobin levels in thalassemia.

Question

In that sentence does it answers this: (Talk a bit about how different genes can be used)

Answer 1

Yes, the sentence mentions that CRISPR-Cas9 could be used on different genes such as HBG1/2 and KLF1 that affect the pathophysiology of thalassemia. It suggests that altering multiple genes could have synergistic effects on foetal haemoglobin levels in thalassemia, showing how different genes can be targeted and modified using this technology.