Arginine

Question

O
2.01
H2N---CH--C----OH

9.02 CH2

CH2

CH2

NH

12.48 C==NH

NH2
________________________________________

9.78 O 2.35

H2N----CH---C----OH

CH3

Glycine

________________________________________

Shown above are images of two amino acids, along with the pKas of each of their titrateable groups.

(a) Calculate the isoelectric point (pI) of the dipeptide Glycine-Arginine.



(b) Calculate the isoelectric point (pI) of the dipeptide Arginine-Glycine.

Answer 1

a) 11.13
b) 10.76

Answer 2

a) 11.13
b) 10.76