An amino acid analysis of the DNA polymerase gene in humans determines that the sequence of the active site is: Val-Gly-Thr-Ser-Cys-Pro. Based on this information, which species below would be considered the most evolutionarily related to humans?(1 point) Responses Species 3: Val-Gly-Thr-Ser-Tyr-Pro Species 3: Val-Gly-Thr-Ser-Tyr-Pro Species 1: Gly-Leu-Ser-Thr-Cys-Pro Species 1: Gly-Leu-Ser-Thr-Cys-Pro Species 4: Leu-Val-Met-Thr-Tyr-Pro Species 4: Leu-Val-Met-Thr-Tyr-Pro Species 2: Val-Gly-Phe-Tyr-Asn-Pro

3 answers

Based on the amino acid sequence of the active site, Species 1: Gly-Leu-Ser-Thr-Cys-Pro would be considered the most evolutionarily related to humans as it shares the most similarities with the human sequence.
explain?
The amino acid sequence of the active site of the DNA polymerase gene in humans is Val-Gly-Thr-Ser-Cys-Pro. When comparing this sequence with the sequences of the potential species listed:

- Species 3: Val-Gly-Thr-Ser-Tyr-Pro has a difference at the fifth position (Cys vs. Tyr). This species is less closely related to humans than Species 1 because it has a different amino acid at a critical position in the active site sequence.
- Species 1: Gly-Leu-Ser-Thr-Cys-Pro has the same amino acids as humans at four out of five positions, with a difference at the first position (Val vs. Gly). Despite this difference, Species 1 shares more similarities with humans in terms of the active site sequence.
- Species 4: Leu-Val-Met-Thr-Tyr-Pro and Species 2: Val-Gly-Phe-Tyr-Asn-Pro have multiple differences compared to the human sequence, making them less evolutionarily related.

Therefore, based on the amino acid sequence of the active site, Species 1 would be considered the most evolutionarily related to humans out of the species listed.