After the middle of the 18th century, what options did Indians still have in responding to the encroachment of settlers? How had Indian behavior changed since the Iroquois mourning wars of the 17th century?

Answer 1

After the French and Indian war?
run !
The wagons then the railroads were coming shortly and all there was realistically was to move to reservations :( There were not enough bullets to shoot all those farmers and ranchers.