The correct choice is:
Prokaryotes tend to only have one chromosome while eukaryotes have many.
This statement accurately reflects the general difference between prokaryotic and eukaryotic chromosomes. Prokaryotic cells typically contain a single, circular chromosome, while eukaryotic cells contain multiple linear chromosomes.
The other statements are incorrect:
- Prokaryotic chromosomes are not wrapped into structures called nucleosomes; that is characteristic of eukaryotic chromosomes.
- Prokaryotic chromosomes are generally smaller than eukaryotic chromosomes.
- Prokaryotic chromosomes are typically circular, while eukaryotic chromosomes are linear.