In a type 1 diabetic patient, the underlying pathophysiology involves the autoimmune destruction of beta cells in the pancreas. This destruction leads to insufficient insulin production, which is why type 1 diabetes is characterized by hyperglycemia due to a lack of insulin.
Based on the options provided, the correct answer would be:
The patient has destruction of beta cells in the pancreas.
The other options are not appropriate in the context of type 1 diabetes:
- Hyperinsulinism would occur if there was excess insulin, which is not typical in type 1 diabetes.
- A high C-peptide level would indicate high levels of endogenous insulin production, which is not the case in type 1 diabetes since the beta cells are destroyed.
- Insulin resistance is more commonly associated with type 2 diabetes, not type 1 diabetes, where the problem is primarily a lack of insulin.