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A patient with hypertension and angina is referred for treat￾ment. Metoprolol and verapamil are among the drugs con￾sidered. Both metoprolol and verapamil are associated with

which one of the following?
(A) Diarrhea
(B) Hypoglycemia
(C) Increased PR interval
(D) Tachycardia
(E) Thyrotoxicosis�

1 answer

(C) Increased PR interval

Both metoprolol and verapamil can cause increased PR interval, although they work through different mechanisms. Metoprolol is a beta-blocker that can slow down the electrical conduction in the heart, leading to prolongation of the PR interval. Verapamil is a calcium channel blocker that can also prolong the PR interval by slowing down conduction through the AV node.