A mutation that causes abnormal cell division can most directly result in skin cancer. Skin cancer is often associated with mutations in genes that regulate cell growth and division, leading to uncontrolled proliferation of skin cells.
Cystic fibrosis and sickle cell anemia are primarily caused by mutations that affect protein function and structure rather than directly causing abnormal cell division. Cystic fibrosis results from mutations in the CFTR gene, and sickle cell anemia is caused by a mutation in the HBB gene, affecting hemoglobin structure in red blood cells.
Clogged arteries are often related to lifestyle factors, genetics, and conditions like atherosclerosis, rather than a direct consequence of mutations causing abnormal cell division.