In this scenario, the correct statement is: The manual is a chromosome.
This is because the manual contains the complete set of instructions needed to build a variety of structures (representing the genetic information), and each specific set of instructions for building a particular structure would correspond to a gene. The interlocking bricks themselves represent the individual components (nucleotides) that make up the DNA, and the structures built from the bricks (proteins) come from the instructions in the manual (chromosome).