To rotate a point \((x, y)\) clockwise 90 degrees about the origin, we use the transformation:
\[ (x, y) \rightarrow (y, -x) \]
Now, we will apply this transformation to both endpoints of the line segment.
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For the first endpoint \((2, -1)\): \[ (2, -1) \rightarrow (-1, -2) \]
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For the second endpoint \((5, -4)\): \[ (5, -4) \rightarrow (-4, -5) \]
So, after rotating the segment 90 degrees clockwise, the new endpoints are \((-1, -2)\) and \((-4, -5)\).
Therefore, the correct response is:
\((−1, −2)\) and \((−4, −5)\).