To rotate a point \((x, y)\) 90 degrees clockwise about the origin, you can use the transformation:
\[ (x, y) \rightarrow (y, -x) \]
Let's apply this transformation to each endpoint of the line segment.
- For the point \((2, -1)\):
\[ (2, -1) \rightarrow (-1, -2) \]
- For the point \((5, -4)\):
\[ (5, -4) \rightarrow (-4, -5) \]
So the new endpoints after rotating the segment 90 degrees clockwise are:
\[ (-1, -2) \quad \text{and} \quad (-4, -5) \]
Therefore, the correct option from the choices given is:
\((-1, -2)\) and \((-4, -5)\).