To find how many times as many pounds the large box weighs compared to the small box, you can divide the weight of the large box by the weight of the small box.
The weight of the large box is 490 pounds, and the weight of the small box is 5 pounds.
Now, divide:
\[ \frac{490}{5} = 98 \]
Thus, the large box weighs 98 times as many pounds as the small box.
The correct response is 98.