A hydrophobic amino acid R group (side group) would be found where in a properly folded protein?

Question

View Available Hint(s)for Part A

Only at one end of a protein chain
Forming hydrogen bonds with other R groups
Forming a peptide bond with the next amino acid in the polypeptide chain
On the inside of the folded chain, away from water molecules
On the outside of the folded chain, exposed to water molecules

Answer 1

A hydrophobic amino acid R group (side group) would be found on the inside of the folded chain, away from water molecules.

In a properly folded protein, hydrophobic (water-repelling) side chains tend to cluster together in the interior of the protein structure, away from the aqueous environment, to minimize their exposure to water. This tendency facilitates the overall stability of the protein's three-dimensional shape.