To find the change in the amount of water in gallons per minute, we first calculate how much water the pump removes in one minute.
The pump removes 250 gallons in 5 minutes. To find the rate of removal per minute, we divide the total gallons by the number of minutes:
\[ \text{Gallons removed per minute} = \frac{250 \text{ gallons}}{5 \text{ minutes}} = 50 \text{ gallons per minute} \]
Since the pump is removing water, the change in the amount of water in the tank is negative. Therefore, the change in the amount of water in gallons in 1 minute is:
\[ -50 \text{ gallons} \]
So the correct response is:
\(-50\)