To find the change in the amount of water in gallons in 1 minute, we first need to determine the rate at which the pump removes water.
The pump removes 250 gallons in 5 minutes. To find the rate per minute, we divide the total gallons removed by the time in minutes:
\[ \text{Rate} = \frac{250 \text{ gallons}}{5 \text{ minutes}} = 50 \text{ gallons per minute} \]
Since the water is being removed from the tank, the change in the amount of water in the tank per minute is negative:
\[ \text{Change in amount of water in 1 minute} = -50 \text{ gallons} \]
Therefore, the correct response is:
−50