A DNA segment has base order CCC ATA GCT. Which copy exhibits a deletion in the first codon triplet and then a substitution mutation?

Responses

CCA ATA GCT
CCA ATA GCT

CCA TAG CT
CCA TAG CT

CCA TAA CT
CCA TAA CT

CCC TAG CT
CCC TAG CT

1 answer

To identify which copy exhibits a deletion in the first codon triplet and then a substitution mutation, we first need to analyze the original DNA sequence and understand the changes represented by each response.

Original DNA segment: CCC ATA GCT

We break it into codon triplets:

  • First codon: CCC
  • Second codon: ATA
  • Third codon: GCT

Now, we need to assess each response:

  1. CCA ATA GCT:

    • Change: CCC → CCA (substitution)
    • No deletion in the first codon.
  2. CCA TAG CT:

    • Change: CCC → CCA (substitution) and deletion of both the second codon (ATA) and the third codon (GCT).
    • Deletion occurred, but this appears to go beyond just a deletion in the first codon.
  3. CCA TAA CT:

    • Change: CCC → CCA (substitution) and deletion of the third codon (GCT).
    • Again, this does not reflect just a deletion in the first codon.
  4. CCC TAG CT:

    • Change: None in the first codon (remains CCC), but the second codon has changed from ATA to TAG (substitution).
    • No deletion has occurred.

Given these analyses, none of the options provided seem to meet the criteria of having a deletion only in the first codon triplet followed by a substitution mutation.

If a deletion was to occur only in the first codon, we would expect something like CC_ATA GCT (removal of one base) and then a substitution. However, since this isn't provided, it seems all examples deviate from your specific request.

If I had to infer, the response that most closely matches a simple change in the first codon with a substitution might be CCA ATA GCT, but it doesn't fit the criteria of containing both a deletion and a substitution as defined.

Please confirm the requirements or provide clarifications if specific answers are indeed required!