Question

A DNA segment has base order AGC TTA TCG. Which copy exhibits a frameshift mutation through deletion?(1 point) Responses AGC TTA TAG AGC TTA TAG AGC TCG AGC TCG AGC TTT CG AGC TTT CG TTA TCG

Answer 1

A frameshift mutation occurs when one or more nucleotides are deleted or inserted into a DNA sequence, which alters the reading frame of the sequence. From the provided original sequence "AGC TTA TCG", we need to identify which of the options has a deletion that shifts the reading frame.

Let's analyze the responses:

1. **AGC TTA TAG** - This doesn't have a deletion; it seems to be a change in the third codon.

2. **AGC TTA TAG** - This is a repetition of the first option and also doesn't have a deletion.

3. **AGC TCG** - This option has a deletion of 2 bases (the second T and the second A), which shifts the reading frame.

4. **AGC TTT CG** - This option has an extra T added, which would not cause a frameshift by deletion.

5. **AGC TTT CG TTA TCG** - This is not a single sequence, as it has an extra segment and does not reflect a simple deletion.

The correct option consistent with a frameshift mutation through deletion would be:
**AGC TCG**.

This deletion results in a change to the downstream codon, which influences the translation of the entire sequence thereafter.