A cell contains DNA damage that causes it to undergo apoptosis before reaching mitosis. This cell had twice the amount of DNA for a cell of this type. During which checkpoint did this cell trigger apoptosis? (1 point)

Question

O G1 Checkpoint
• G2 Checkpoint
• M Checkpoint
• No checkpoint meets these criteria.

Answer 1

The cell you described had twice the amount of DNA, which indicates that it likely underwent DNA replication but did not successfully progress through the cell cycle due to DNA damage. Since the damage triggers apoptosis before mitosis, it suggests that the cell was assessed for DNA damage after the S phase but before entering mitosis.

Given this scenario, the apoptosis was most likely triggered at the G2 Checkpoint. The G2 checkpoint checks for DNA damage and ensures that the cell is ready to enter mitosis (M phase). If there is unresolved DNA damage, the cell can undergo apoptosis at this checkpoint.

So the correct answer is: • G2 Checkpoint