Asked by Help Please
Given a study of 9804 overweight or obese subjects with preexisting cardiovascular disease and/or type 2 diabetes.
Subjects randomly assigned to subitramine (4906 subjects) or a placebo (4898 subjects) in a double-blind fashion.
Primary outcome was observed in 561 subjects in the subitramine group and 490 subjects in the placebo group.
Find the proportion of subjects experiencing the primary outcome for both the subitramine and placebo groups
I found subritramine proportion = 0.11 and placebo proportion = 0.10.
***Can we safely use the large sample confidence interval for comparing the proportions of subitramine and placebo subjects who experienced the primary outcome? explain.
this is where I need help. Thank you.
Subjects randomly assigned to subitramine (4906 subjects) or a placebo (4898 subjects) in a double-blind fashion.
Primary outcome was observed in 561 subjects in the subitramine group and 490 subjects in the placebo group.
Find the proportion of subjects experiencing the primary outcome for both the subitramine and placebo groups
I found subritramine proportion = 0.11 and placebo proportion = 0.10.
***Can we safely use the large sample confidence interval for comparing the proportions of subitramine and placebo subjects who experienced the primary outcome? explain.
this is where I need help. Thank you.
Answers
Answered by
MathGuru
Yes, you should be able to use the large sample confidence interval due to the size of the samples in the study. The larger the sample size, the more you can safely approximate the normal distribution.
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