Question

I have a method using HPLC (high performance liquid chromatography).

It states that a 4.6 x 150mm,3um column should be used. (stationary phase : octadecylsilyl silica gel).

I have a 4.6 x 100mm,2.7um column, silica-based, bonded-phase (non-polar) column.

Can you advise if these 2 can be considered equivalent?

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