Question
Calculate the pH of the solute in an aqueous solution of 0.0047 M codeine, if the pKa of itsconjugate acid is 8.21.
What is the percentage protonation of the solute?
What is the percentage protonation of the solute?
Answers
DrBob222
If we all codeine, C, then the hydrolysis is
C + HOH ==> HC^+ + OH^-
Kb = (Kw/Ka) = (OH^-)^2/(C)
Substitute into the Kb expression and solve for OH^-, convert to pOH, then to pH.
C + HOH ==> HC^+ + OH^-
Kb = (Kw/Ka) = (OH^-)^2/(C)
Substitute into the Kb expression and solve for OH^-, convert to pOH, then to pH.