Can anyone help ..

Question

State the functional groups that the BZP and TFMPP in Party Pills and MDMA have in common.

ph //-\\/CF3
/ [[ ]]
[ N ] \\ // < Benzine
[
[ N ] / N \
\H/ [ ]
\ N /
(BZP) H (TFMPP)

/ \
0 0
\- /
//-\\ Benzene
\ - /
\_/Me
\NHMe MDMA Ectasy

Me is used as an abbreviation for the methyl; CH 3 group

I think they all have the amine NH functional group in common is that right ???

Have been asked to suggest why party pill may have similar pharmacological activity to to amphetamines ???

Thanks

Sorry about the layout !

Answer 1

It is hard to draw structures on here!

BZP is benzyl piperazine. It has a secondar amine, tertiary amine and a benzene ring (if you are counting this as a FG).

3-Trifluoromethylphenylpiperazine (TFMPP) has the same functional groups. The trifluoromethyl group is not normally considered to be a functional group.

MDMA (3,4-Methylenedioxymethamphetamine) or ecstacy has a secondary amine group, a benzene ring (if you count this) and methylenedioxy (which are ether functional groups).

So in common they have a secondary amine group and the benzene ring.

They all have similar structures to the basic amphetmine structure

http://en.wikipedia.org/wiki/Amphetamines

It is easier if you can make models of thse and compare them.

Answer 2

Thank you Dr Russ !