Question

Patient 1 and patient 2 both had a transplant. Which most likely explains why patient 1 had a successful transplant and patient 2 did not?
Patient 1 underwent tissue typing, but patient 2 was tested for antigen compatibility.
Patient 1 underwent long-term immunosuppressive therapy, but patient 2 was given immunosuppressants during the surgery.
Patient 1 began an exercise routine after surgery and maintained it for the rest of his life, but patient 2 led a more sedentary lifestyle.
Patient 1 followed a healthy diet low in salt and fat, but patient 2 did not monitor his diet.

Answer 1

Patient 1 underwent long-term immunosuppressive therapy, but patient 2 was given immunosuppressants during the surgery.

Explanation: Transplanted organs are targeted by the recipient's immune system and require ongoing immunosuppression to prevent acute and chronic rejection. Giving immunosuppressants only during surgery would not prevent later immune responses against the graft; long-term therapy is needed to maintain tolerance.