Question

Which is important to note when preparing a dose of pembrolizumab and berahyaluronidase alfa-pmph for administration?

a.
The prepared syringes should be stored in the refrigerator.
b.
The needle should be changed immediately before injection.
c.
The drug comes in 1 vial size, with a different dose withdrawn depending on whether it is every 3-week vs every 6-week dosing.
d.
The drug is manufactured in prefilled syringes.

Answer 1

b.

Change the needle immediately before injection. Drawing the product from the vial can dull or contaminate the needle, so manufacturers and aseptic technique guidance recommend replacing the draw-up needle with a fresh needle for the patient injection.