Question

What cause tachycardiac at corpulmonale

Answer 1

for corpulmonale what is the function of biospsy

Answer 2

I assume you mean “cor pulmonale” (right‑heart dysfunction from lung disease). Tachycardia in cor pulmonale can come from several overlapping mechanisms:

Main physiologic mechanisms
- Compensatory sympathetic activation: RV failure → reduced left ventricular preload and lower cardiac output → baroreceptor stimulation and increased sympathetic tone (catecholamines) → sinus tachycardia to maintain systemic perfusion.
- Hypoxemia and hypercapnia: peripheral and central chemoreceptor activation in lung disease (COPD, pulmonary embolism) raises heart rate.
- Neurohormonal activation: RAAS and other humoral responses in chronic heart failure support sympathetic drive and tachycardia.
- RV ischemia and stretch: elevated RV pressure/volume stretches atria and ventricle, promoting arrhythmias.
- Arrhythmogenic substrate: chronic right atrial enlargement predisposes to supraventricular arrhythmias (atrial fibrillation/flutter, multifocal atrial tachycardia).

Acute vs chronic picture
- Acute cor pulmonale (e.g., massive pulmonary embolism): marked sympathetic surge, severe hypoxia, and abrupt reduction in LV filling → prominent sinus tachycardia and may progress to unstable arrhythmias.
- Chronic cor pulmonale (e.g., pulmonary hypertension, COPD): more persistent compensatory tachycardia and higher risk of atrial arrhythmias from chamber dilation.

Other contributors
- Medications (beta‑agonist bronchodilators, theophylline) and fever, pain or anemia can increase heart rate.

Clinical implications / what to evaluate
- Distinguish sinus tachycardia (compensation) from pathologic arrhythmia (AF, MAT) with ECG.
- Check oxygenation, electrolytes, volume status, and echocardiogram to assess RV function.
- Treat underlying cause (oxygen, diuresis if volume overloaded, treat PE, rate/rhythm control if arrhythmia).

If you want, tell me whether you’re asking about acute or chronic cor pulmonale or about diagnosis/treatment and I can give more specific steps.